Unique and Complex Andrological Operations

The patient is 77 years old with urinary incontinence after the prostate’s transurethral resection (minimally invasive burning).

The world standard in solving this problem is installing an artificial sphincter — a cuff that locks the urethra when pumping. When releasing the valve, the patient can urinate.

The only problem is that such devices are manufactured in Switzerland and the United States, cost about 7 thousand dollars, and are financially unaffordable for Ukrainians, especially retirement age.

To this patient, endourethrally, we removed rough scars in the prostate and at the border of the prostate and urethra injected a mixture of collagen and neuroblasts grown from THEIR OWN  (autologous) stem cells.

A week after the operation, the patient feels a significant improvement. We expect to see the full effect in 3 months when neuroblasts will germinate, and the patient will be able to control his sphincter as much as possible.

In addition to the absence of an artificial sphincter, many hours of surgery, and a long operation, a positive point was a significant reduction in the patient’s costs and a minimally invasive procedure.

Patient from America with Peyronie’s disease: severe plaque curving the penis.

The gold standard for Peyronie’s disease is corporoplasty, in which the excised plaque is replaced by a bovine pericardium, which aligns the penis.

However, the patient wanted to thicken the penis at the same time. Unfortunately, you cannot put two implants (bovine pericardium and a prolene mesh for thickening), as non-engraftment and rejection can occur.

For this patient, we grew mesothelium (a thin film) from his stem cells,  with which we closed the defect of the protein-membrane and aligned the penis, and under the skin, we installed a prolene mesh, which added almost 4 cm to the circumference.

A patient with a stricture of the external urethra. A hole with a diameter of a needle ear opened under the head of the penis.

There are two standard techniques: meatotomy, in which the hole is formed even lower along the trunk (usually used in elderly patients who are no longer sexually active), or complex urethroplasty using the epithelium of the cheek.

Many patients are afraid of gross defects of the oral cavity when taking the epithelium from the inner surface of the cheek. Therefore, we first grew his epithelium from his stem cells and implanted him during surgery.

In addition to saving time, reducing the operational risk, this technique has a significant advantage: from the epithelium of the cheek, you can take only a flap up to 6 * 2 cm, which may not be enough to replace extended urethral strictures, while your epithelium can be grown almost any size, replacing the urethral stricture of any length.